#13 Transgenic laboratory animals in hypertension research

  • M van der Giet Freie Universitat Berlin, University Hospital Benjamin Franklin, Institute of Clinical Pharmacology
  • S Hoffman Freie Universitat Berlin, University Hospital Benjamin Franklin, Institute of Clinical Pharmacology
  • H Urata Freie Universitat Berlin, University Hospital Benjamin Franklin, Institute of Clinical Pharmacology
  • D Ganten Max-Delbruck Center for Molecular Medicine
  • M Paul Max-Delbruck Center for Molecular Medicine

Abstract

In the last years generation of genetically modi fied animals by transgenic techniques is an increasingly important tool in the field of hypertension research. Transgenic animals give the opportunity to analyse gene function and regulation in
VlVO.
In this review we want to give an overview of the applications of transgenesis to hypertension research, reviewing the most important transgenic lines which have been generated to date. Recent data about these transgenic animal lines is summarized. Finally we will give some information about new transgenic models and consider the future possibilities for hypertension research.

Published
2019-09-26
Section
Articles